Functional respiratory imaging in relation to classical outcome measures in cystic fibrosis: a cross-sectional study.

ABSTRACT:

Background

Functional Respiratory Imaging (FRI) combines HRCT scans with computational fluid dynamics to provide objective and quantitative information about lung structure and function. FRI has proven its value in pulmonary diseases such as COPD and asthma, but limited studies have focused on cystic fibrosis (CF). This study aims to investigate the relation of multiple FRI parameters to validated imaging parameters and classical respiratory outcomes in a CF population.

Methods

CF patients aged > 5 years scheduled for a chest CT were recruited in a cross-sectional study. FRI outcomes included regional airway volume, airway wall volume, airway resistance, lobar volume, air trapping and pulmonary blood distribution. Besides FRI, CT scans were independently evaluated by 2 reade

SUBMITTER: Lauwers E 

PROVIDER: S-EPMC8336350 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature