Dissociation between 2-[¹⁸F]fluoro-2-deoxy-D-glucose positron emission computed tomography, ultrasound and clinical assessments in patients with non-severe rheumatoid arthritis, including remission.

ABSTRACT:

Background

Inflammation of patients joints with severe disease activity of rheumatoid arthritis (RA) has already been visualized and quantified by 2-[¹⁸F]fluoro-2-deoxy-D-glucose positron emission computed tomography ([¹⁸F] FDG PET/CT), but little is known about the metabolic status and its relationship with clinical and ultrasonography (US) metrology in patients with low/moderate activity or in remission.

Methods

Clinical assessments [based on 28-joint disease activity score (DAS₂₈-CRP) and Clinical Disease Activity Index (CDAI)], [¹⁸F] FDG PET/CT, US and X-ray were performed on 63 RA patients classified into remission or low/moderate or severe disease activity groups. PET/CT was visually and then semi-quantitatively analysed by d

SUBMITTER: Rinkin C 

PROVIDER: S-EPMC8336401 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature