Fetal exposure to bisphenols and phthalates and childhood bone mass: a population-based prospective cohort study.

ABSTRACT:

Background

Exposure to bisphenols and phthalates might influence bone health. We hypothesized that exposure to bisphenols and phthalates during fetal life has persistent effects on bone development.

Objectives

To analyze the associations of fetal exposure to bisphenols and phthalates with bone health in school-aged children.

Methods

Among 1,362 mother-child pairs participating in a population-based cohort study, we measured maternal urinary concentrations of bisphenols and phthalates at first, second and third trimester with high performance liquid chromatography electrospray ionization-tandem mass spectrometry. Total body bone mineral density (BMD) and bone area (BA) were measured using dual-energy X-ray absorptiometry (DXA) at 6 and 10 years, and were both used to c

SUBMITTER: van Zwol-Janssens C 

PROVIDER: S-EPMC8336628 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature