Statins and the progression of age-related macular degeneration in the United States.

ABSTRACT:

Purpose

To study the effect of statin exposure on the progression from non-exudative to exudative age-related macular degeneration (AMD).

Methods

Retrospective cohort study of commercially insured patients diagnosed with non-exudative AMD (n = 231,888) from 2007 to 2015. Time-to-event analysis of the association between exposure to lipid-lowering medications and time from non-exudative AMD to exudative AMD diagnosis was conducted. Outcome measures included progression to exudative AMD, indicated by diagnosis codes for exudative AMD or procedural codes for intravitreal injections.

Results

In the year before and after first AMD diagnosis, 11,330 patients were continuously prescribed lipid-lowering medications and 31,627 patients did not take any lipid-lowering medicatio

SUBMITTER: Ludwig CA 

PROVIDER: S-EPMC8336881 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature