Healthful plant-based dietary patterns, genetic risk of obesity, and cardiovascular risk in the UK biobank study.

ABSTRACT:

Background & aims

People with a higher genetic risk for obesity are more likely to develop cardiovascular disease (CVD), and healthy plant-based dietary patterns may be associated with decreased risks of obesity and cardiovascular events. We investigated whether adherence to healthy plant-foods-rich dietary patterns might attenuate risks of obesity and related cardiovascular abnormalities for people at genetically higher risk of obesity.

Methods

This study included 121,799 middle-aged adults in UK Biobank who were initially free of metabolic diseases and cancer. We calculated a healthful plant-based diet index (hPDI) based on 17 major food groups as well as a genetic risk score (GRS) for obesity consisting of body mass index (BMI)-associated variants. The incidence of cardio

SUBMITTER: Heianza Y 

PROVIDER: S-EPMC8338907 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature