Rationale and design of the HINODE study: Heart failure indication and sudden cardiac death prevention trial Japan.

ABSTRACT:

Background

Randomized trials in Western countries have provided evidence that prophylactic implantable cardioverter-defibrillator (ICD) therapy reduces mortality in heart failure (HF) patients with reduced left ventricular ejection fraction. However, the risk of life-threatening ventricular arrhythmias in Japanese HF patients sharing similar risk factors is still unknown.

Methods

The Heart Failure Indication and Sudden Cardiac Death Prevention Trial Japan trial (NCT03185832) is a prospective, multicenter registry designed to collect data on ventricular arrhythmia, HF events, and mortality in Japanese HF patients. Japanese patients with HF and 2-5 predefined risk factors who were indicated for cardiac device implantation based on European Society of Cardiology guidelines were

SUBMITTER: Yamasaki H 

PROVIDER: S-EPMC8339090 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature