Duration of labor among women with thromboembolic events: A Swedish register study.

ABSTRACT:

Introduction

Inflammation is central to initiation of labor and coagulation is closely interlinked with inflammation. Low-molecular-weight-heparin (LMWH) promotes inflammatory cervical remodeling, myometrium contractility and has been associated with shorter duration of labor.

Material and methods

This was a cohort study of 136,661 deliveries 2013-2017, identified in the Swedish Pregnancy Register with prospectively collected pregnancy and labor characteristics. Information of duration of labor was retrieved from the electronic birth records and analyzed with Cox proportional hazard regressions according to previous or current thromboembolic disease (overall) with or without LMWH treatment with non-exposed as reference.

Results

The crude hazard ratio for vaginal deliv

SUBMITTER: Hesselman S 

PROVIDER: S-EPMC8339223 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature