Disease Burden, Risk Factors, and Recent Trends of Liver Cancer: A Global Country-Level Analysis.

ABSTRACT:

Background

This study aimed to evaluate the updated disease burden, risk factors, and temporal trends of liver cancer based on age, sex, and country.

Methods

We estimated the incidence of liver cancer and its attribution to hepatitis B virus (HBV) and hepatitis C virus (HCV) in 2018 based on the Global Cancer Observatory and World Health Organization (WHO) Cancer Causes database. We extracted the prevalence of risk factors from the WHO Global Health Observatory to examine the associations by weighted linear regression. The trend analysis used data from the Cancer Incidence in Five Continents and the WHO mortality database from 48 countries. Temporal patterns of incidence and mortality were calculated using average annual percent change (AAPC) by joinpoint regression a

SUBMITTER: Huang J 

PROVIDER: S-EPMC8339459 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature