Molecular networks of the FOXP2 transcription factor in the brain.
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ABSTRACT:
SUBMITTER: den Hoed J
PROVIDER: S-EPMC8339667 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
Molecular networks of the FOXP2 transcription factor in the brain.
den Hoed Joery J Devaraju Karthikeyan K Fisher Simon E SE
EMBO reports 20210714 8
The discovery of the FOXP2 transcription factor, and its implication in a rare severe human speech and language disorder, has led to two decades of empirical studies focused on uncovering its roles in the brain using a range of in vitro and in vivo methods. Here, we discuss what we have learned about the regulation of FOXP2, its downstream effectors, and its modes of action as a transcription factor in brain development and function, providing an integrated overview of what is currently known ab ...[more]
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