Anatomical location and number of metastatic lymph nodes for prognosis of non-small cell lung cancer.

ABSTRACT:

Background

The nodal classification of lung cancer is determined by the anatomical location of metastatic lymph nodes (mLNs). However, prognosis can be heterogeneous at the same nodal stage, and the current classification system requires improvement. Therefore, we investigated the correlation between the number of mLNs and prognosis in patients with non-small cell lung cancer.

Methods

Using a multicenter database in Japan, we retrospectively reviewed the records of patients who underwent complete resection for lung cancer between 2010 and 2016. Kaplan-Meier curves were used to determine recurrence-free and overall survival. Multivariate analyses were performed using the Cox proportional hazards model.

Results

We included 1,567 patients in this study. We could show a s

SUBMITTER: Samejima J 

PROVIDER: S-EPMC8339744 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature