Early pharmacologic conversion of atrial fibrillation after off-pump coronary artery bypass grafting.

ABSTRACT:

Background

The aim of this study was to evaluate the efficacy of early amiodarone-based pharmacological cardioversion for postoperative atrial fibrillation (POAF) following off-pump coronary bypass grafting (OPCAB).

Methods

A total of 507 patients who underwent OPCAB between 2015 and 2017 were categorized into POAF (n=94) and no-POAF (n=413) groups. Patients in the POAF group were treated according to the following institutional protocol: 150 mg loading dose of intravenous amiodarone, followed by oral administration with sequential maintenance doses at 600, 400, and 200 mg per day. If sinus rhythm was restored before discharge, patients were discharged without amiodarone or anticoagulants, except for dual antiplatelets.

Results

Before discharge at index hospitalizatio

SUBMITTER: Lee H 

PROVIDER: S-EPMC8339786 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature