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Risk factors predicting the occurrence of metachronous ovarian metastasis of gastric cancer.


ABSTRACT:

Background

Ovarian metastasis following radical gastrectomy, also known as metachronous ovarian metastasis (MOM), pose a significant threat to the long-term survival of female gastric cancer (GC) patients. However, a mechanism to identify and characterize operated patients at high risk of developing MOM remains unknown. This retrospective study aimed to identify risk factors for the occurrence of MOM based on the profiling of clinicopathological parameters and expression of sex hormone receptors (SHR) of operated GC patients with and without ovarian relapse.

Methods

The clinicopathological data of 1,055 female GC patients from two medical centers who underwent surgery between January 2011 and December 2015 were reviewed. A total of 378 patients with and without the occurrenc

SUBMITTER: Gao J 

PROVIDER: S-EPMC8339813 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature