Neutrophil to lymphocyte ratio and adverse clinical outcomes in patients with ischemic stroke.

ABSTRACT:

Background

Neutrophils and lymphocytes mediate differential inflammatory responses after ischemic stroke and have different effects on patients' clinical outcomes. Several studies have used the neutrophil to lymphocyte ratio (NLR) as a prognostic indicator for ischemic stroke; however, some limitations remain.

Methods

We derived data from the Third China National Stroke Registry. The NLR is defined as neutrophil count/lymphocyte count. Patients included in the study were classified into four groups by NLR quartiles. Odds ratios (ORs) of adverse clinical outcomes were calculated with the lowest quartile group as the reference category. We plotted receiver operating characteristic (ROC) curves of NLR for adverse clinical outcomes and calculated area under the curve (AUC) value

SUBMITTER: Quan K 

PROVIDER: S-EPMC8339844 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature