Comparison of Radiomic Features in a Diverse Cohort of Patients With Pancreatic Ductal Adenocarcinomas.

ABSTRACT:

Background

Significant racial disparities in pancreatic cancer incidence and mortality rates exist, with the highest rates in African Americans compared to Non-Hispanic Whites and Hispanic/Latinx populations. Computer-derived quantitative imaging or "radiomic" features may serve as non-invasive surrogates for underlying biological factors and heterogeneity that characterize pancreatic tumors from African Americans, yet studies are lacking in this area. The objective of this pilot study was to determine if the radiomic tumor profile extracted from pretreatment computed tomography (CT) images differs between African Americans, Non-Hispanic Whites, and Hispanic/Latinx with pancreatic cancer.

Methods

We evaluated a retrospective cohort of 71 pancreatic cancer cases (23 African A

SUBMITTER: Permuth JB 

PROVIDER: S-EPMC8339963 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature