Cognitive predictors of longitudinal positive symptom course in clinical high risk for psychosis.

ABSTRACT:

Background

Clinical High Risk (CHS) for psychosis is a state in which positive symptoms are predominant but do not reach a level of severity that fulfils the criteria for a psychotic episode. The aim of this study has been to investigate whether cognition in subjects with newly detected CHR affects the longitudinal development of positive symptoms.

Methods

Fifty-three CHR individuals fulfilling the criteria for attenuated positive syndrome in the Structural Interview for Prodromal Syndromes (SIPS) were included. At inclusion, all participants completed a neurocognitive battery consisting of tests measuring attention, verbal memory, verbal fluency, executive functions and general intelligence. Cognitive domain z-scores were defined by contrasting with observed scores of a gro

SUBMITTER: Aase I 

PROVIDER: S-EPMC8340303 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature