Metabolomics in Diabetic Retinopathy: A Systematic Review.

ABSTRACT:

Purpose

Diabetic retinopathy (DR), a common microvascular complication of diabetes, is the leading cause of acquired blindness in the working-age population. Individuals with diabetes still develop DR despite appropriate glycemic and blood pressure control, highlighting the pressing need to identify useful biomarkers for risk stratification. The purpose of this review is to systematically summarize potential metabolic biomarkers and pathways of DR, which could facilitate developing an understanding of the disease mechanisms, as well as new therapeutic measures.

Methods

We searched PubMed and Web of Science for relevant metabolomics studies on humans published before September 30, 2020. Information regarding authors, title, publication date, study subjects, analytical platfor

SUBMITTER: Hou XW 

PROVIDER: S-EPMC8340662 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature