Clinical features and mechanism of liver injury in patients with mild or moderate coronavirus disease 2019.

ABSTRACT:

Background and aim

We aimed to identify clinical features that suggest that coronavirus disease 2019 (COVID-19) should be a differential diagnosis in patients presenting with a chief complaint of fever and abnormal liver function.

Methods

We retrospectively studied the presence or absence of abnormal liver function in 216 patients diagnosed with mild-moderate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection between February and September 2020.

Results

Abnormal liver function was observed in 51 patients with mild-moderate COVID-19. The median peak aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were 57.5, 75.5, and 332.5 U/L, respectively. The median number of days from symptom onset to peak

SUBMITTER: Gomi K 

PROVIDER: S-EPMC8341189 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature