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The clinical practice of ulcerative colitis in elderly patients: An investigation using a nationwide database in Japan.


ABSTRACT:

Background and aim

The number of elderly patients with ulcerative colitis (UC) is increasing worldwide. The clinical practice of associated treatment is still unclear. Therefore, we aimed to analyze clinical treatment realities and mortality in elderly and non-elderly patients with UC.

Methods

We collected UC patients' data using the diagnosis procedure combination (DPC) database system and divided eligible patients into elderly (≥65 years) and non-elderly (≤64 years) groups. We investigated and compared their therapeutic histories (medical treatments vs. surgery). Logistic regression analysis was conducted to identify clinical factors affecting surgery and in-hospital death in each group.

Results

The rates of systemic steroid injection, molecular targeting dru

SUBMITTER: Moroi R 

PROVIDER: S-EPMC8341191 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature