Prevalence of unculturable bacteria in the periapical abscess: A systematic review and meta-analysis.

ABSTRACT:

Objective

To assess the prevalence of unculturable bacteria in periapical abscess, radicular cyst, and periapical granuloma.

Methods

PubMed, Scopus, Science Direct, and Ovid databases were systematically searched from January 1990 to May 2020. All the included studies were cross-sectional design. The risk of bias was assessed using Joanna Briggs Institute check-list. Heterogeneity was described using meta-regression and mixed-effects model for lesion, country, and sequence technique moderators. Funnel plot and unweighted Egger's regression test were used to estimate the publication bias. Microbiome data on diversity, abundance, and frequency of unculturable bacteria in the periapical lesions were reviewed, analysed, and the principal component analysis (PCA) was performed.

SUBMITTER: Altaie AM 

PROVIDER: S-EPMC8341601 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature