Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study.

ABSTRACT:

Purpose

While it is well documented that maternal adverse exposures contribute to a series defects on offspring health according to the Developmental Origins of Health and Disease (DOHaD) theory, paternal evidence is still insufficient. Advanced paternal age is associated with multiple metabolism and psychiatric disorders. Birth weight is the most direct marker to evaluate fetal growth. Therefore, we designed this study to explore the association between paternal age and birth weight among infants born at term and preterm (<37 weeks gestation).

Methods

A large retrospective study was conducted using population-based hospital data from January 2015 to December 2019 that included 69,964 cases of singleton infant births with complete paternal age data. The primary outcome was i

SUBMITTER: Mao Y 

PROVIDER: S-EPMC8341720 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature