Epidemiology of childhood tuberculosis after ceasing universal Bacillus Calmette-Guerin vaccination.

ABSTRACT: Universal Bacillus Calmette-Guérin (BCG) vaccination is recommended in countries with high tuberculosis (TB) burden. Nevertheless, several countries have ceased universal BCG vaccination over the past 40 years, with scarce comparative epidemiological analyses regarding childhood TB after the policy change. We analysed data on childhood TB in countries that ceased universal BCG vaccination. Data sources included national/international databases, published papers, annual TB reports, and public health authority websites. Childhood TB notification rate increased in one of seven countries with available data. Pulmonary TB and TB lymphadenitis were the main causes of increasing childhood cases, while changes in severe forms of TB cases were minor. Maintaining high vaccine coverage for the target

SUBMITTER: Kobayashi S 

PROVIDER: S-EPMC8342465 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature