Elevated Neurobehavioral Responses to Negative Social Interactions in Women With Bulimia Nervosa.

ABSTRACT:

Background

Bulimia nervosa (BN) is a complex psychiatric illness that includes binge-purge behaviors and a belief that one's value as a person depends on body shape and weight. Social pressure strongly influences the development and maintenance of BN, but how this manifests neurobiologically within an individual remains unknown. We used a computational psychiatry approach to evaluate neural mechanisms underlying social interactions in BN.

Methods

Behavioral and functional magnetic resonance imaging data were collected from 24 women with BN and 26 healthy comparison women using an iterated social exchange game. Data were sorted round by round based on whether the mathematically computed social signals indicated an improving (positive reciprocity) or deteriorating (negative re

SUBMITTER: Luo Y 

PROVIDER: S-EPMC8342632 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature