Global longitudinal strain as a prognostic marker in cardiac resynchronisation therapy: A systematic review.

ABSTRACT:

Purpose

Cardiac resynchronisation therapy (CRT) has proven mortality benefits for heart failure patients with moderate to severe systolic left ventricular dysfunction and evidence of a left bundle branch block. Determining responders to this therapy can be difficult due to the presence of myocardial fibrosis and scar. Left ventricular global longitudinal strain (LV GLS) is a robust and sensitive measure of myocardial function and fibrosis that has significant prognostic value for a plethora of cardiac pathologies. Our aim was to perform a systematic review of the value of LV GLS for predicting outcomes in patients undergoing CRT.

Methods

A systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PR

SUBMITTER: Appadurai V 

PROVIDER: S-EPMC8342974 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature