US deceased kidney transplantation: Estimated GFR, donor age and KDPI association with graft survival.

ABSTRACT:

Background

Despite a significant shortage of kidneys for transplantation in the US, kidneys from older deceased donors are infrequently transplanted. This is primarily over concern of graft quality and transplant durability.

Methods

The US national transplant database (2000-2018) was assessed for deceased donor kidney transplant patient and graft survival, graft durability and stratified by donor age (<65 years>), Kidney Donor Profile Index (KDPI) and estimated glomerual filtration rate (GFR) one year post-transplantation (eGFR-1) were calculated.

Findings

Recipients of kidneys transplanted from deceased donors >65 years had a lower eGFR-1, (median 39 ml/min) than recipients of younger donor kidneys (median 54 ml/min). However, death-censored graft survival, stratifie

SUBMITTER: Pruett TL 

PROVIDER: S-EPMC8343266 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature