Familial Contributions to the Association Between Low Birth Weight and Risk of CKD in Adult Life.

ABSTRACT:

Introduction

Previous studies have revealed that individuals with low birth weight (LBW) have higher risk of chronic kidney disease (CKD) and that LBW and CKD cluster in families. This study investigates how familial factors affect the association between birth-related risk markers and risk of CKD.

Methods

The Medical Birth Registry (MBR) of Norway has registered all births in Norway since 1967. Sibling data were available through the Norwegian Population Registry. The Norwegian Patient Registry has registered diagnostic codes for all admissions and outpatient visits to Norwegian hospitals since 2008. Data from these registries were linked. Risk of CKD according to whether the individual himself or at least one of his siblings had LBW was analyzed using logistic regression s

SUBMITTER: Gjerde A 

PROVIDER: S-EPMC8343716 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature