Association of Admission, Nadir, and Terminal Donor Creatinine With Kidney Transplantation Outcomes.

ABSTRACT:

Introduction

When assessing deceased kidney donors, a key factor in organ acceptance and allocation is donor kidney function. It is unclear whether terminal, admission, or the highest of terminal and admission donor estimated glomerular filtration rate (eGFR) most predicts recipient outcomes.

Methods

We examined which measurement best predicts outcomes. Using data from the Australia and New Zealand Organ Donation and Dialysis and Transplant Registries, we included adult recipients of deceased donor kidney-only transplants over 2003 to 2019. We compared the 3 different exposure variables of admission, terminal, or highest eGFR. We created logistic regression models for delayed graft function (DGF), multilinear regression models for 6- and 12-month eGFR, and Cox proportional h

SUBMITTER: Irish GL 

PROVIDER: S-EPMC8343793 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature