Relationship between adverse childhood experiences and Alzheimer's disease: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Alzheimer's disease has a high prevalence and a substantial impact on society, as well as the individual. Findings from clinical studies to date, suggest that multiple factors are likely to contribute to the variability seen in the progression of Alzheimer's disease. However, despite this accumulating evidence, current identified factors do not explain the full extent of disease onset. Thus, the role of additional factors needs to be explored further.One such factor is exposure to adverse childhood experiences. However, the degree of this association is unknown. This systematic review will examine the literature investigating the associations between adverse childhood experiences and the risk of Alzheimer's disease.

Methods and analysis

Articles investigating as

SUBMITTER: Corney KB 

PROVIDER: S-EPMC8344279 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature