Intubation Setting, Aspiration, and Ventilator-Associated Conditions.

ABSTRACT:

Background

Patients experience endotracheal intubation in various settings with wide-ranging risks for postintubation complications such as aspiration and ventilator-associated conditions.

Objectives

To evaluate associations between intubation setting, presence of aspiration biomarkers, and clinical outcomes.

Methods

This study is a subanalysis of data from the NO-ASPIRATE single-blinded randomized clinical trial. Data were prospectively collected for 513 adult patients intubated within 24 hours of enrollment. Patients with documented aspiration events at intubation were excluded. In the NO-ASPIRATE trial, intervention patients received enhanced oropharyngeal suctioning every 4 hours and control patients received sham suctioning. Tracheal specimens for α-amylase and p

SUBMITTER: Talbert S 

PROVIDER: S-EPMC8344364 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature