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Helicobacter pylori co-infection with Epstein-Barr virus and the risk of developing gastric adenocarcinoma at an early age: Observational study infectious agents and cancer.


ABSTRACT:

Background

Gastric cancer (GC) is one of the leading causes of morbidity and mortality worldwide. The onset and progression of gastric cancer are attributed to numerous triggers, these triggers may be infection of the gastric epithelium by Helicobacter pylori (H. pylori), or by Epstein-Barr virus (EBV). Both agents can establish a lifelong persistent infection in the host, leading to chronic inflammation, which also contributes to cancer development. Objective: The objective of this study is to present the status of co-infection with H. pylori and EBV and the risk of developing adenocarcinoma at an early age in the population of Grand Casablanca.

Methods

In this study, 100 gastric tissue samples from patients with gastric cancer were examined for detecti

SUBMITTER: Rihane FE 

PROVIDER: S-EPMC8346356 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature