The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata.

ABSTRACT: Genetic variance is not equal for all multivariate combinations of traits. This inequality, in which some combinations of traits have abundant genetic variation while others have very little, biases the rate and direction of multivariate phenotypic evolution. However, we still understand little about what causes genetic variance to differ among trait combinations. Here, we investigate the relative roles of mutation and selection in determining the genetic variance of multivariate phenotypes. We accumulated mutations in an outbred population of Drosophila serrata and analyzed wing shape and size traits for over 35,000 flies to simultaneously estimate the additive genetic and additive mutational (co)variances. This experimental design allowed us to gain insight into the phenotypic eff

SUBMITTER: Dugand RJ 

PROVIDER: S-EPMC8346878 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature