Ontology highlight
ABSTRACT:
SUBMITTER: Baracaldo-Santamaria D
PROVIDER: S-EPMC8347245 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Baracaldo-Santamaría Daniela D Llinás-Caballero Kevin K Corso-Ramirez Julián Miguel JM Restrepo Carlos Martín CM Dominguez-Dominguez Camilo Alberto CA Fonseca-Mendoza Dora Janeth DJ Calderon-Ospina Carlos Alberto CA
International journal of molecular sciences 20210728 15
Long QT syndromes can be either acquired or congenital. Drugs are one of the many etiologies that may induce acquired long QT syndrome. In fact, many drugs frequently used in the clinical setting are a known risk factor for a prolonged QT interval, thus increasing the chances of developing torsade de pointes. The molecular mechanisms involved in the prolongation of the QT interval are common to most medications. However, there is considerable inter-individual variability in drug response, thus m ...[more]