Effect of d-limonene and its derivatives on breast cancer in human trials: a scoping review and narrative synthesis.

ABSTRACT:

Background

D-limonene and its derivatives have demonstrated potential chemopreventive and anticancer activity in preclinical and clinical studies. The aim of this scoping review was to assess and critically appraise current literature on the effect of these bioactive citrus peel compounds on breast cancer in human trials and to identify knowledge gaps for exploration in future studies.

Methods

This study followed a scoping review framework. Peer-reviewed journal articles were included if they reported the effect of d-limonene or its derivatives on breast cancer in human subjects. Articles were retrieved from academic databases - PubMed, EMBASE, CINAHL, Web of Science, and Cochrane reviews - and iteratively through review of bibliographies of relevant manuscripts. Titles and

SUBMITTER: Chebet JJ 

PROVIDER: S-EPMC8349000 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature