Biomarkers and Fatty Fish Intake: A Randomized Controlled Trial in Norwegian Preschool Children.

ABSTRACT:

Background

Biomarkers such as omega-3 (n-3) PUFAs, urinary iodine concentration (UIC), 1-methylhistidine (1-MH), and trimethylamine N-oxide (TMAO) have been associated with fish intake in observational studies, but data from children in randomized controlled trials are limited.

Objectives

The objective of this exploratory analysis was to investigate the effects of fatty fish intake compared with meat intake on various biomarkers in preschool children.

Methods

We randomly allocated (1:1) 232 children, aged 4 to 6 y, from 13 kindergartens. The children received lunch meals of either fatty fish (herring/mackerel) or meat (chicken/lamb/beef) 3 times a week for 16 wk. We analyzed 86 biomarkers in plasma (n = 207), serum (n = 195), RBCs (n = 211), urine (n = 200), and hair

SUBMITTER: Solvik BS 

PROVIDER: S-EPMC8349119 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature