Different Food Sources of Fructose-Containing Sugars and Fasting Blood Uric Acid Levels: A Systematic Review and Meta-Analysis of Controlled Feeding Trials.

ABSTRACT:

Background

Although fructose as a source of excess calories increases uric acid, the effect of the food matrix is unclear.

Objectives

To assess the effects of fructose-containing sugars by food source at different levels of energy control on uric acid, we conducted a systematic review and meta-analysis of controlled trials.

Methods

MEDLINE, Embase, and the Cochrane Library were searched (through 11 January 2021) for trials ≥ 7 days. We prespecified 4 trial designs by energy control: substitution (energy-matched replacement of sugars in diets); addition (excess energy from sugars added to diets); subtraction (energy from sugars subtracted from diets); and ad libitum (energy from sugars freely replaced in diets) designs. Independent reviewers (≥2) extracted data and ass

SUBMITTER: Ayoub-Charette S 

PROVIDER: S-EPMC8349131 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature