Dataset Information

Treatment Success Across Different Levels of Preoperative Disease Burden: Stratified Two-Year Outcomes from the Pivotal Trial of iStent inject ^® Trabecular Micro-Bypass in Primary Open-Angle Glaucoma and Cataract.

ABSTRACT:

Purpose

To examine effectiveness outcomes stratified by preoperative disease burden in the pivotal trial of iStent inject ^® with cataract surgery (INJ) vs cataract surgery alone (CS).

Materials and methods

Prospective, 3:1 randomized, single-masked, concurrently-controlled, multicenter trial enrolling 505 subjects with cataract and mild-to-moderate primary open-angle glaucoma who underwent iStent inject implantation with phacoemulsification or phacoemulsification alone, and were followed for 2 years including annual medication washouts. Post hoc stratification was completed for baseline mean diurnal intraocular pressure (BL DIOP; Low-DIOP <25mmHg, Mid-DIOP ≥25 to <30 mmHg, High-DIOP ≥30mmHg) and preoperative medication burden (Low-Med 1 medication, M

SUBMITTER: Singh IP

PROVIDER: S-EPMC8349204 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

ACCESS DATA

Dataset Information

Treatment Success Across Different Levels of Preoperative Disease Burden: Stratified Two-Year Outcomes from the Pivotal Trial of iStent inject ^® Trabecular Micro-Bypass in Primary Open-Angle Glaucoma and Cataract.

Purpose

Materials and methods

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Treatment Success Across Different Levels of Preoperative Disease Burden: Stratified Two-Year Outcomes from the Pivotal Trial of iStent inject ® Trabecular Micro-Bypass in Primary Open-Angle Glaucoma and Cataract.

Purpose

Materials and methods

OmicsDI is part of the ELIXIR infrastructure

Tweets

Treatment Success Across Different Levels of Preoperative Disease Burden: Stratified Two-Year Outcomes from the Pivotal Trial of iStent inject ^® Trabecular Micro-Bypass in Primary Open-Angle Glaucoma and Cataract.