Initial Clinical Experience with the Biodegradable Absnow^TM Device for Percutaneous Closure of Atrial Septal Defect: A 3-Year Follow-Up.

ABSTRACT:

Objective

We reported the 3-year follow-up results of initial clinical experience with the Absnow^TM device, a novel biodegradable occluder for percutaneous closure of atrial septal defect (ASD).

Background

The Absnow^TM device is a total biodegradable septal occluder with double-disc poly-L-lactic acid (PLLA) framework and PLLA membranes intergraded into the device to ensure its biodegradability, clinical safety, and efficacy.

Methods

Five pediatric patients were enrolled from May to June 2018 in our institution and were followed up for 3 years. A clinical evaluation and transthoracic echocardiography were performed at 24 hr, 1 month, 3 months, 6 months, 12 months, and yearly after implantation. Primary endpoints were a composite clinical success,

SUBMITTER: Li Y 

PROVIDER: S-EPMC8349294 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature