High Prevalence of Low Serum Biologically Active Testosterone in Older Male Veterans.

ABSTRACT:

Objectives

Assess the prevalence of hypogonadism in older male Veterans by comparing direct measurements of total testosterone (T) and bioavailable testosterone (BioT) versus indirect BioT values derived from existing and newly developed regression analyses.

Design

Cohort study.

Setting

Malcom Randall VA Medical Center, Gainesville, FL.

Participants

Community-dwelling male Veterans aged 60 and older (n = 203).

Measurements

Total T, BioT, albumin, sex hormone-binding globulin (SHBG), and body mass index were evaluated. Blood values were assessed via liquid chromatography-tandem mass spectrometry (LC-MS/MS) and clinical or commercially available immunoassays to compare accuracy among assessment techniques. Existing and newly developed multiple regression a

SUBMITTER: Conover CF 

PROVIDER: S-EPMC8349505 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature