Defining oligometastatic non-small cell lung cancer: concept versus biology, a literature review.

ABSTRACT:

Objective

In this review, the concept of (synchronous) oligometastatic disease in patients with non-oncogene-driven non-small cell lung cancer (NSCLC) will be placed in the context of tumor biology and metastatic growth patterns. We will also provide considerations for clinical practice and future perspectives, which will ultimately lead to better patient selection and oligometastatic disease outcome.

Background

The treatment landscape of metastasized NSCLC has moved from "one-size fits all" to a personalized approach. Prognosis has traditionally been poor but new treatment options, such as immunotherapy and targeted therapy, brighten future perspectives. Another emerging development is the recognition of patients with so-called "oligometastatic" state of disease. Oligometas

SUBMITTER: Mentink JF 

PROVIDER: S-EPMC8350082 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature