Risk-score model to predict prognosis of malignant airway obstruction after interventional bronchoscopy.

ABSTRACT:

Background

Interventional bronchoscopy exhibits substantial effects for patients with malignant airway obstruction (MAO), while little information is available regarding the potential prognostic factors for these patients.

Methods

Between October 31, 2016, and July 31, 2019, a total of 150 patients undergoing interventional bronchoscopy and histologically-confirmed MAO were collected, in which 112 eligible participants formed the cohort for survival study. External validation cohort from another independent institution comprised 33 MAO patients with therapeutic bronchoscopy. The least absolute shrinkage and selection operator regression (LASSO) was applied to the model development dataset for selecting features correlated with MAO survival for inclusion in the Cox regression

SUBMITTER: Jiang M 

PROVIDER: S-EPMC8350098 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature