Diagnostic and prognostic biomarkers in oligometastatic non-small cell lung cancer: a literature review.

ABSTRACT:

Objective

This review aims to summarize the possibilities of recently discovered molecular diagnostic techniques in lung cancer, by evaluating their impact on diagnosis, monitoring, and prognosis in oligometastatic disease.

Background

Oligometastatic non-small cell lung cancer (OM-NSCLC) is currently defined based on morphological rather than biological features. Major advances in the detection of molecular biomarkers in cell-free tumoral DNA and the models of oncogene addiction make as feasible an early diagnosis and guide the therapeutic decision-making progress to improve the prognosis.

Methods

This narrative review EXAMINES current approaches of diagnosis, monitoring, and prognosis of OM-NSCLC and describes the fast-evolving therapeutic scenario of this disease. W

SUBMITTER: Cortinovis D 

PROVIDER: S-EPMC8350105 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature