Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC8350166 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Li HaiXia H Zheng Chao C Han Jinming J Zhu Jie J Liu Shan S Jin Tao T
Frontiers in cellular neuroscience 20210726
The programmed cell death protein-1/programmed death ligand-1 (PD-1/PD-L1) axis is a widely studied immune checkpoint that modulates signaling pathways related to T cell activation. The use of PD-1/PD-L1 inhibitors is a promising immune therapy strategy for cancer patients. However, individuals treated with PD-1/PD-L1 inhibitors may develop immune-related adverse events due to excessive immune reactions. Multiple sclerosis (MS) is a chronic demyelinating and neurodegenerative disease of the cent ...[more]