Non-alcoholic fatty liver disease and sarcopenia additively increase mortality: a Korean nationwide survey.

ABSTRACT:

Background

Sarcopenia is an independent risk factor not only for advanced-stage non-alcoholic fatty liver disease (NAFLD) but also for mortality. We investigated the association of sarcopenia and/or NAFLD with mortality among the Korean general population.

Methods

Individuals aged 35-75 years without any history of cancer, ischaemic heart disease, ischaemic stroke, or secondary causes of chronic liver disease were selected from the Korean National Health and Nutrition Examination Surveys from 2008 to 2015. Their mortality data until December 2018 were retrieved from the National Death Registry. NAFLD and sarcopenia were defined by hepatic steatosis index and appendicular skeletal muscle mass divided by body mass index (BMI), respectively.

Results

A total of 28 060 sub

SUBMITTER: Moon JH 

PROVIDER: S-EPMC8350204 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature