Impact of age and metabolic syndrome-like components on prostate cancer development: a nationwide population-based cohort study.

ABSTRACT:

Background

Because of the contradictory results, more epidemiologic data is needed to determine if metabolic syndrome is a risk factor for developing prostate cancer. This study investigated whether metabolic syndrome-like components affect the incidence of prostate cancer in a Korean population.

Methods

Men over 50 years of age who underwent health examinations in 2009 were followed until December 2015 (n=1,917,430) using National Health Insurance System data. Subjects were divided into three groups according to the number of metabolic syndrome-like components. The predictive accuracy of age for prostate cancer was assessed by the Youden index and multivariate adjusted Cox regression analysis was used to analyze the effect of metabolic syndrome-like components on prostate c

SUBMITTER: Choi JB 

PROVIDER: S-EPMC8350233 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature