Oligometastatic prostate cancer: definition and the role of local and systemic therapy: a narrative review.

ABSTRACT: The definition of oligometastatic prostate cancer (OMPC) includes a heterogenous group of disease states, mostly defined by the number and site of metastases, which seems to be biologically different to widespread tumors. Evidence suggests a substantial survival benefit for this subgroup of limited metastatic burden which is currently seen as a potentially curable disease and therefore with an increasing interest in the scientific community. As there is still no consensus on the definition of OMPC, commonly used criteria are based on the CHAARTED and LATITUDE trials. The management algorithms for these patients were rapidly changing in the past decade due to recent data with a paradigm shift to a multimodal intensification of the treatment by the availability of combinations of hormonal th

SUBMITTER: Mahjoub S 

PROVIDER: S-EPMC8350250 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature