Biological properties of andrographolide, an active ingredient of Andrographis Paniculata: a narrative review.

ABSTRACT: Andrographolide is a labdane diterpenoid isolated from Andrographis paniculata and traditionally used in Chinese and Indian medicine. Reported effects include anti-bacterial, anti-inflammatory and anti-cancer functions. Most of the studies support the hypothesis that andrographolide supplementation stimulates immune system, so the observed effects migh in fact be secondary to the stimulation of defense reactions. As andrographolide is involved in regulation of inflammation, it is not surprising that it is also evaluated in inflammation-mediated diseases such as ulcerative colitis. Anticancer effects of the andrographolide have been tested on various cancer panels. Colon cancer, breast cancer, and head and neck carcinomas were the most investigated, followed by prostate cancer and gl

SUBMITTER: Vetvicka V 

PROVIDER: S-EPMC8350652 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature