Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study.

ABSTRACT: The presence of circulating microbiome in blood has been reported in both physiological and pathological conditions, although its origins, identities and function remain to be elucidated. This study aimed to investigate the presence of blood microbiome by quantitative real-time PCRs targeting the 16S rRNA gene. To our knowledge, this is the first study in which the circulating microbiome has been analyzed in such a large sample of individuals since the study was carried out on 1285 Randomly recruited Age-Stratified Individuals from the General population (RASIG). The samples came from several different European countries recruited within the EU Project MARK-AGE in which a series of clinical biochemical parameters were determined. The results obtained reveal an association between microbial

SUBMITTER: D'Aquila P 

PROVIDER: S-EPMC8350766 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature