Sepsis-Associated Acute Kidney Disease and Long-term Kidney Outcomes.

ABSTRACT:

Rationale & objective

Sepsis-associated acute kidney injury often leads to acute kidney disease (AKD), predisposing patients to long-term complications such as chronic kidney disease (CKD), kidney failure with replacement therapy (KFRT), or mortality. Risk stratification of patients with AKD represents an opportunity to assist with prognostication of long-term kidney complications.

Study design

Single-center retrospective cohort.

Setting & participants

6,290 critically ill patients admitted to the intensive care unit with severe sepsis or septic shock. Patients were separated into cohorts based on incident acute kidney injury or not, and survivors identified who were alive and free of KFRT up to 90 days.

Predictors

AKD stage (0A, 0C, or ≥1) using the last serum

SUBMITTER: Flannery AH 

PROVIDER: S-EPMC8350838 | biostudies-literature | 2021 Jul-Aug

REPOSITORIES: biostudies-literature