COSMOS next generation - A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals.

ABSTRACT: The COSMOS Database (DB) was originally established to provide reliable data for cosmetics-related chemicals within the COSMOS Project funded as part of the SEURAT-1 Research Initiative. The database has subsequently been maintained and developed further into COSMOS Next Generation (NG), a combination of database and in silico tools, essential components of a knowledge base. COSMOS DB provided a cosmetics inventory as well as other regulatory inventories, accompanied by assessment results and in vitro and in vivo toxicity data. In addition to data content curation, much effort was dedicated to data governance - data authorisation, characterisation of quality, documentation of meta information, and control of data use. Through this effort, COSMOS DB was able to merge an

SUBMITTER: Yang C 

PROVIDER: S-EPMC8351204 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature