Association of ERCC gene polymorphism with osteosarcoma risk.

ABSTRACT:

Background

The relationship between ERCC gene polymorphism and osteosarcoma risk / overall survival of osteosarcoma is still conflicting, and this meta-analysis was performed to assess these associations.

Material and methods

The association studies were identified from PubMed, and eligible reports were included and calculated using meta-analysis method.

Results

Four studies were included for the association of ERCC gene polymorphism with osteosarcoma risk, and nine studies were recruited into this meta-analysis for the relationship between ERCC gene polymorphism and overall survival of osteosarcoma. The meta-analysis indicated that ERCC1 rs3212986 (8092 C>A) gene polymorphism, ERCC1 rs11615 (19007 T>C) gene polymorphism, ERCC2 rs1799793 (A>G) gene polymorphism, ERCC2

SUBMITTER: Wang G 

PROVIDER: S-EPMC8351846 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature