Influence of HLA-B*5701 on 20 year survival rate among patients living with HIV.

ABSTRACT:

Background

The life expectancy of people living with HIV (PLWH) remains shorter than that of the general population, despite significant improvement in the recent years. Mortality in HIV-infected individuals may be associated with a higher viral load at of diagnosis, a lower CD4 count, or clinical variables such as sex or route of transmission. This article investigated the role of the HLA-B*5701 varian on mortality among PLWH.

Methods

Material for the analysis consist of the data of 2,393 patients for whom the HLA-B*57 variant was known. Those patients were followed under the care of the Infectious Diseases Hospital in Warsaw (n = 1555) and the Clinic of Acquired Immunodeficiency of the Pomeranian Medical University in Szczecin (n = 838). Factors such as age, gender, date o

SUBMITTER: Aksak-Was BJ 

PROVIDER: S-EPMC8351921 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature